MIF: Most Interesting Factor

Yale Medicine Magazine, 2010 - Winter

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MIF: Most Interesting Factor
Second Opinion

by Richard Bucala, M.D., Ph.D., professor of medicine (rheumatology), pathology, and epidemiology (microbial diseases) (World Scientific Publishing Company) This book describes the biology of the MIF (migration inhibitory factor) gene. Human genetic studies have identified allelic forms of the MIF gene, and high-expression alleles have been associated with rheumatoid arthritis, asthma severity, sarcoidosis, atopy, inflammatory bowel disease, and other inflammatory and infectious maladies. The book also discusses the role of the MIF factor itself as a therapeutic target.

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Richard Bucala, MD, PhD
Waldemar Von Zedtwitz Professor of Medicine (Rheumatology) and Professor of Pathology and of Epidemiology (Microbial Diseases); Chief, Rheumatology, Allergy, & Immunology; Rheumatologist in Chief, Rheumatology; Affiliated Faculty, Yale Institute for Global Health

Outside the bounds of polite conversation

Second Opinion

MIF: Most Interesting Factor

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