Thirteen Yale-affiliated biotechnology companies are located in and around New Haven, and close to a dozen more businesses—the majority are expected to locate in the city—are now in development with assistance from Yale’s Office of Cooperative Research. The existing New Haven-based companies are clustered in several locations in the city center and in nearby Branford.
Publicly traded companies
Alexion Pharmaceuticals
Drug development for cardiovascular and autoimmune disorders, inflammation and cancer
CuraGen Corporation
Genomics-based drug discovery and development
Genaissance Pharmaceuticals
Population genomics and personalized medicine
Neurogen Corporation
Drug discovery and development for psychiatric, metabolic and inflammatory disorders
Vion Pharmaceuticals
Anti-cancer drug discovery, development and commercialization
Companies developed by the Office of Cooperative Research
Founder’s names in italics
Achillion Pharmaceuticals
Antiviral therapeutic discovery and development
Yung-Chi Cheng
Agilix
Agriculture gene discovery
Paul Lizardi
Cellular Genomics Inc.
Proteomics and functional genomics
Ira Mellman
L2 Diagnostics
Lyme disease diagnostics
Erol Fikrig, Joseph Craft and Richard Flavell
Molecular Staging Inc.
Molecular diagnostics based on rolling circle amplification technology
David Ward and Sherman Weissman
PhytoCeutica
Pharmaceutical development of traditional Chinese medicine
Yung-Chi Cheng
polyGenomics (now merged with Molecular Staging Inc.)
Disease-associated genetic mutations
Sherman Weissman and David Ward
RadioTracer
Development of novel brain imaging agents
Ronald Baldwin and Robert Innis
Recombinant Technologies
Production and distribution of novel research reagents
Pazhani Sundaram
Companies in development
GasNet
Anesthesiology Internet commerce Web site
Keith Ruskin and Charlotte Clark
TurboGenomics
Bioinformatic tools for genomics
Gregory Gardiner
Phoenix Drug Discovery
Disease-associated targets for drug development
Gregory Gardiner
UltraBiotics
Development of novel antibiotics
John Swartley
Axotech
Regeneration of CNS neurons
Stephen Strittmatter and Jeffery Kocsis
Rib-X Designs
Development of antibiotics and novel drug targets based on ribosome inhibition
Thomas Steitz and Peter Moore
Archemix
Molecular sensors for drug discovery
Ronald Breaker
Chemasense
Odorants to modify insect and pest behavior
John Carlson
Epigenix Inc.
Transgenic animals and functional genomics
Frank Ruddle and Adrian Hayday
Protometrix
Informatic tools for protein expression analysis
Michael Snyder and Sherman Weissman
VaxInnate
Vaccine cassettes for rapid development of novel vaccines
Ruslan Medzhitov and Richard Flavell
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